| Nant-le-Grand | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason Nant-le-Grand (Meuse).svg |
| Arrondissement: | Bar-le-Duc |
| Canton: | Ancerville |
| Insee: | 55373 |
| Postal Code: | 55500 |
| Mayor: | Marc Déprez[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CA Bar-le-Duc - Sud Meuse |
| Coordinates: | 48.6786°N 5.2261°W |
| Elevation M: | 249 |
| Elevation Min M: | 233 |
| Elevation Max M: | 351 |
| Area Km2: | 11.26 |
Nant-le-Grand is a commune in the Meuse department in Grand Est in north-eastern France.