The Jury of Nandi Awards announced Nandi Awards for the year 2010 on 5 August 2011 at Film Development Corporation.Radhakrishna directed Vedam won the best film award . Nandamuri Balakrishna has won Best actor Award for Simha and Nithya Menon has won the best actress award for her debut movie Ala Modalaindi.
| Category | Winner | Film | Nandi Type | |
|---|---|---|---|---|
| Vedam | Vedam | Gold | ||
| Second Best Feature Film | Ganga Putrulu | Ganga Putrulu | Silver | |
| Third Best Feature Film | Prasthanam | Prasthanam | Bronze | |
| Nandi Award for Akkineni Award for best home-viewing feature film | Andari Bandhuvaya | Silver | ||
| Best Popular Film for Providing Wholesome Entertainment | Maryada Ramanna | Maryada Ramanna | Gold | |
| Sarojini Devi Award for a Film on National Integration | Parama Veera Chakra | Parama Veera Chakra | Gold | |
| Gold | ||||
| Second Best Children's Film | Little Buddha | Little Buddha | Copper | |
| Best Director for a Children's Film | Copper | |||
| Best Documentary Film | Advaitham | Advaitham | Gold | |
| Second Best Documentary Film | Freedom park | Freedom park | Silver | |
| First best educational film | Golden | |||
| Second best educational film | Copper | |||
| Best Director | P Sunil Kumae Reddy | Ganga Putrulu | Silver | |
| Best Actor | N.Bala Krishna | Simha | Silver | |
| Best Actress | Nitya Menon | Ala Modalaindi | Silver | |
| Best Supporting Actor | Sai Kumar | Prasthanam | Copper | |
| Best Supporting Actress | Pragati | Yemaindi Ee Vela | Copper | |
| Best Character Actor | AVS | Kothimooka | Copper | |
| Alasyam Amrutam | Copper | |||
| Best Female Comedian | Jhansi | Simha | Copper | |
| Best Villain | Nagineedu | Marada Ramanna | Copper | |
| Best Child Actor | Master Bharat | Bindaas | Copper | |
| Best Child Actress | Copper | |||
| Ala Modalaindi | Copper | |||
| Best Screenplay Writer | Ye Maaya Chesave(YMC) | Copper | ||
| Best Story Writer | RP Patnaik | Broker | Copper | |
| P Sunil Kumar Reddy | Ganga Putrulu | Copper | ||
| Best Lyricist | N Siddareddy | Veera Telangana | Copper | |
| Prasad Murella | Namo Venkatesa | Copper | ||
| Best Music Director | Chakri | Simha | Copper | |
| Maryada Ramanna | Copper | |||
| Best Female Playback Singer | Pranavi | Sneha Geetam | Copper | |
| Best Editor | Kotagiri Venkateswara Rao | Darling | Copper | |
| Best Art Director | Ashok | Varudu | Copper | |
| Best Choreographer | Prem Rakshit | Adurs(Ye Pilla) | Copper | |
| Best Audiographer | Radhakrishna | Brindavanam | Copper | |
| Best Costume Designer | Sriram & Sri Kumar | Varudu | Copper | |
| Best Makeup Artist | Sri Gangadhar | Brahmalokam to Yamalokam via Bhoolokam | Copper | |
| Best Fight Master | Sri Sekhar | Manasara | Copper | |
| Best Male Dubbing Artist | RPM Raju | Darling | Copper | |
| Best Female Dubbing Artist | Chinmayi | Ye Maaya Chesave(YMC) | Copper | |
| Sri Alagar Swamy | Varudu | Copper | ||
| Special Jury Award | Allu Arjun | Vedam | Copper | |
| Special Jury Award | Samantha | YMC | Copper | |
| Special Jury Award | Chandra Siddhartha | Andari Bandhuvaya | Copper | |
| Special Jury Award | Manoj Manchu | Bindaas | Copper | |
| Special Jury Award | Sunil | Maryada Ramanna | Copper | |
| Special Jury Award | Sreeramulu | Vedam | Copper | |
| Nandi Award for Best Book on Telugu Cinema(Books, posters, etc.) | Dr. Paidipala | Dr. Paidipala Telugu Cine Geya Kavula Charitra | Copper | |
| Best Film Critic on Telugu Cinema | Chakravarthy | Copper |