| Nancy Kleckner | |
| Workplaces: | Harvard University |
| Alma Mater: | Harvard University, Massachusetts Institute of Technology |
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| Doctoral Advisor: | Ethan Signer |
| Doctoral Students: | Victoria Lundblad |
| Known For: | chromosome mechanics |
| Awards: | Thomas Hunt Morgan Medal (2016) |
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Nancy Kleckner is the Herchel Smith Professor of Molecular Biology at Harvard University and principal investigator at the Kleckner Laboratory at Harvard University.
Nancy Kleckner worked with Matt Meselson as an undergraduate at Harvard University, earning her degree in 1968. She then moved on to do her PhD at Massachusetts Institute of Technology working with Ethan Signer on the genetics of lambda phage and DNA replication.[1] She did a postdoc under David Botstein at Princeton University in 1974.
Kleckner returned to Harvard as a professor in 1977 and was awarded tenure in 1985.[2] Her first graduate student at Harvard was Victoria Lundblad, who discovered the gene-enzyme systems of yeast that control formation of telomeres.[3]
Her work in transposons and mutagenesis has been largely productive, and led her to study the physical mechanism of chromosome replication. She discovered SeqA, a protein involved in initiation of DNA replication.
Currently, she runs the Kleckner Lab[4] at Harvard University which performs research related to chromosome and membrane mechanics.