Nucleoporin 160 Explained

Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.^{[1] [2]}

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM]^[2]

Further reading

• Nagase T, Seki N, Ishikawa K, etal . Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. . DNA Res. . 3 . 1 . 17–24 . 1996 . 8724849 . 10.1093/dnares/3.1.17 . free .
• Belgareh N, Rabut G, Baï SW, etal . An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. . J. Cell Biol. . 154 . 6 . 1147–60 . 2001 . 11564755 . 10.1083/jcb.200101081 . 2150808 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Loïodice I, Alves A, Rabut G, etal . The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. . Mol. Biol. Cell . 15 . 7 . 3333–44 . 2005 . 15146057 . 10.1091/mbc.E03-12-0878 . 452587 .
• Lehner B, Sanderson CM . A protein interaction framework for human mRNA degradation. . Genome Res. . 14 . 7 . 1315–23 . 2004 . 15231747 . 10.1101/gr.2122004 . 442147 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Nousiainen M, Silljé HH, Sauer G, etal . Phosphoproteome analysis of the human mitotic spindle. . Proc. Natl. Acad. Sci. U.S.A. . 103 . 14 . 5391–6 . 2006 . 16565220 . 10.1073/pnas.0507066103 . 1459365 . 2006PNAS..103.5391N . free .
• Orjalo AV, Arnaoutov A, Shen Z, etal . The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. . Mol. Biol. Cell . 17 . 9 . 3806–18 . 2006 . 16807356 . 10.1091/mbc.E05-11-1061 . 1593160 .
• Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Ewing RM, Chu P, Elisma F, etal . Large-scale mapping of human protein-protein interactions by mass spectrometry. . Mol. Syst. Biol. . 3 . 1. 89 . 2007 . 17353931 . 10.1038/msb4100134 . 1847948 .
• Glavy JS, Krutchinsky AN, Cristea IM, etal . Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex. . Proc. Natl. Acad. Sci. U.S.A. . 104 . 10 . 3811–6 . 2007 . 17360435 . 10.1073/pnas.0700058104 . 1820666 . 2007PNAS..104.3811G . free .
• Zuccolo M, Alves A, Galy V, etal . The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. . EMBO J. . 26 . 7 . 1853–64 . 2007 . 17363900 . 10.1038/sj.emboj.7601642 . 1847668 .

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Nuclear pore complex protein Nup160

Notes and References

1. Vasu S, Shah S, Orjalo A, Park M, Fischer WH, Forbes DJ . Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export . J Cell Biol . 155 . 3 . 339–54 . Oct 2001 . 11684705 . 2150853 . 10.1083/jcb.200108007 .
2. Web site: Entrez Gene: NUP160 nucleoporin 160kDa.