NF-kappa-B-activating protein explained

NF-kappa-B-activating protein is a protein that in humans is encoded by the NKAP gene.^{[1] [2]}

Further reading

• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Ghiorzo P, Mantelli M, Gargiulo S, etal . Inverse correlation between p16INK4A expression and NF-kappaB activation in melanoma progression . Hum. Pathol. . 35 . 8 . 1029–37 . 2004 . 15297971 . 10.1016/j.humpath.2004.02.017 .
• Beausoleil SA, Jedrychowski M, Schwartz D, etal . Large-scale characterization of HeLa cell nuclear phosphoproteins . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . free .
• Ballif BA, Villén J, Beausoleil SA, etal . Phosphoproteomic analysis of the developing mouse brain . Mol. Cell. Proteomics . 3 . 11 . 1093–101 . 2005 . 15345747 . 10.1074/mcp.M400085-MCP200 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Gevaert K, Staes A, Van Damme J, etal . Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC . Proteomics . 5 . 14 . 3589–99 . 2006 . 16097034 . 10.1002/pmic.200401217 . 895879 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . free .
• Zhande R, Karsan A . Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL . Am. J. Physiol. Heart Circ. Physiol. . 292 . 5 . H2467–74 . 2007 . 17237249 . 10.1152/ajpheart.00649.2006 . 15775587 .

Notes and References

1. Chen D, Li Z, Yang Q, Zhang J, Zhai Z, Shu HB . Identification of a nuclear protein that promotes NF-kappaB activation . Biochem Biophys Res Commun . 310 . 3 . 720–4 . Oct 2003 . 14550261 . 10.1016/j.bbrc.2003.09.074 .
2. Web site: Entrez Gene: NKAP NF-kappaB activating protein.