| State: | NC |
| Type: | NC |
| Route: | 6 |
| Map: | NC 6 Map.png |
| Length Mi: | 8.5 |
| Direction A: | West |
| Direction B: | East |
| Terminus A: | in west Greensboro |
| Junction: | southeast of downtown Greensboro |
| Terminus B: | in east Greensboro |
| Counties: | Guilford |
| Established: | 1959[1] |
| Decommissioned: | 2005 |
| Previous Type: | NC |
| Previous Route: | 5 |
| Next Type: | NC |
| Next Route: | 7 |
North Carolina Highway 6 (NC 6) was an 8adj=midNaNadj=mid North Carolina state highway. It ran entirely in Guilford County and served primarily to connect Interstate 40 (I-40) and Business I-85 (I-85 Bus.) commuters in Greensboro. It was decommissioned in 2005.
The western terminus of NC 6 was at I-40 and U.S. Route 421 (US 421) at I-40's exit 216 in West Greensboro. The interchange only allowed for eastbound I-40 / southbound US 421 traffic to enter eastbound NC 6 and vice versa. From there, NC 6 traveled east Patterson Street with a speed limit of 45mi/h, having an interchange with Merrit Drive, then to Patterson's only traffic signal at Holden Road. It continued east to Patterson's end at the Greensboro Coliseum with a speed limit of 35mi/h. NC 6 then turned to the northeast and followed High Point Road onto Lee Street. NC 6 intersected O'Henry Boulevard (U.S. Route 29 (US 29), US 70, and US 220). The state highway continued east bending slightly to the south before ending at I-40 and I-85 Bus. at their exit 224.