NADPH—cytochrome-c2 reductase explained

In enzymology, a NADPH—cytochrome-c2 reductase is an enzyme that catalyzes the chemical reaction

NADPH + 2 ferricytochrome c₂

NADP⁺ + H⁺ + 2 ferrocytochrome c₂

Thus, the two substrates of this enzyme are NADPH and ferricytochrome c2, whereas its 3 products are NADP⁺, H⁺, and ferrocytochrome c2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a heme protein as acceptor. The systematic name of this enzyme class is NADPH:ferricytochrome-c2 oxidoreductase. Other names in common use include cytochrome c2 reductase (reduced nicotinamide adenine dinucleotide, phosphate), cytochrome c2 reductase (reduced nicotinamide adenine dinucleotide, and phosphate, NADPH). It employs one cofactor, FAD.

References

• Sabo DJ, Orlando JA . 1968 . Isolation, purification, and some properties of reduced nicotinamide adenine dinucleotide phosphate-cytochrome C2 reductase from Rhodopseudomonas spheroides . J. Biol. Chem. . 243 . 3742 - 9 . 4385431 . 13 .