| Mule Key | |
| Nickname: | --> |
| Pushpin Map: | Florida#Caribbean |
| Pushpin Label Position: | left |
| Pushpin Relief: | 1 |
| Pushpin Map Caption: | Mule Key |
| Coordinates: | 24.562°N -81.8618°W |
| Location: | Gulf of Mexico |
| Archipelago: | Florida Keys |
| Waterbody: | Florida Straits |
| Country Admin Divisions Title: | State |
| Country Admin Divisions: | Florida |
| Country Admin Divisions Title 1: | County |
| Country Admin Divisions 1: | Monroe |
Mule Key is an island in the Florida Keys in Monroe County, Florida, United States. It is within the boundaries of the Key West National Wildlife Refuge.
Located in the Outlying Islands of the Florida Keys, it is the easternmost of the Mule Keys that are 9 miles (15 km) west of Key West.[1]