| Moose Brook | |
| Pushpin Map: | New Hampshire#USA |
| Pushpin Map Size: | 250 px |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New Hampshire |
| Subdivision Type3: | County |
| Subdivision Name3: | Coos |
| Subdivision Type4: | Towns |
| Subdivision Name4: | Randolph, Gorham |
| Length: | 4.7miles |
| Source1: | Ice Gulch |
| Source1 Location: | Randolph |
| Source1 Coordinates: | 44.4194°N -71.2822°W |
| Source1 Elevation: | 744m (2,441feet) |
| Mouth: | Androscoggin River |
| Mouth Location: | Gorham |
| Mouth Coordinates: | 44.4019°N -71.1967°W |
| Mouth Elevation: | 778feet |
| Tributaries Left: | Perkins Brook |
Moose Brook is a 4.7adj=midNaNadj=mid[1] stream in northern New Hampshire in the United States. It is a tributary of the Androscoggin River, which flows south and east into Maine, joining the Kennebec River near the Atlantic Ocean.
Moose Brook rises in the town of Randolph, in Ice Gulch, a sharp notch in the Crescent Range in the northern White Mountains. The floor of Ice Gulch is filled with giant, angular boulders under which ice can stay present throughout the summer. Moose Brook exits the gulch by dropping over Peboamauk Fall, then continues east through Moose Brook State Park to reach the Androscoggin River in the town of Gorham, New Hampshire. The brook should not be confused with the Moose River, which enters the Androscoggin less than one mile downstream of Moose Brook.