Monometacrine Explained

Cas Number:4757-49-7
Pubchem:145765
Chemspiderid:128589
Unii:3FDC82890Y
Chembl:2104752
Synonyms:Desmethyldimetacrine; Nordimetacrine; N-Desmethyldimetacrine; SD-735; NSC-100296
Iupac Name:3-(9,9-dimethylacridin-10-yl)-N-methylpropan-1-amine
C:19
H:24
N:2
Smiles:CC1(C2=CC=CC=C2N(C3=CC=CC=C31)CCCNC)C
Stdinchi:1S/C19H24N2/c1-19(2)15-9-4-6-11-17(15)21(14-8-13-20-3)18-12-7-5-10-16(18)19/h4-7,9-12,20H,8,13-14H2,1-3H3
Stdinchikey:PGSOFANFWNSSRA-UHFFFAOYSA-N

Monometacrine (; developmental code name SD-735), also known as desmethyldimetacrine, is a drug of the tricyclic family described as an antidepressant which was never marketed.[1] [2] [3] It was first described in the literature by 1966. The drug is the N-desmethyl analogue of dimetacrine and is a metabolite of dimetacrine.

Notes and References

  1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer US . 2014 . 978-1-4757-2085-3 . 20 October 2024 . 835.
  2. Book: Negwer M, Scharnow HG . Organic-chemical Drugs and Their Synonyms: An International Survey . Wiley-VCH . v. 3 . 2001 . 978-3-527-30247-5 . 20 October 2024 . 1788.
  3. Web site: Monometacrine . Inxight Drugs . National Center for Advancing Translational Sciences (NCATS) . 20 October 2024.