| State: | MO |
| Type: | Route |
| Route: | 190 |
| Map Custom: | yes |
| Map Notes: | MO 190 highlighted in red |
| Length Mi: | 35.166 |
| Direction A: | West |
| Terminus A: | west of Trenton |
| Direction B: | East |
| Terminus B: | north of Chillicothe |
| Previous Type: | MO |
| Previous Route: | 187 |
| Next Type: | MO |
| Next Route: | 202 |
Route 190 is a highway in northern Missouri. Its eastern (or southern) terminus is at U.S. Route 65 north of Chillicothe; its western (or northern) terminus is at Route 146 west of Trenton.
The northern terminus of Route 190 is at an intersection with Missouri Route 146 outside of the unincorporated community of Edinburg, Missouri. It then heads west and makes several somewhat sharp turns before heading south to Jamesport, Missouri. North of Jamesport, Route 190 intersects with Missouri Route 6. Route 190 has a short concurrency with Supplemental Route F in Jamesport and then It then heads south towards Lock Springs, Missouri. After going through Lock Springs, Route 190 heads east towards Chillicothe, Missouri and ends at its southern terminus at U.S. Route 65