| State: | MO |
| Type: | Route |
| Route: | 177 |
| Length Mi: | 23.489 |
| Direction A: | South |
| Terminus A: | in Cape Girardeau |
| Direction B: | North |
| Terminus B: | at Fruitland |
| Previous Type: | MO |
| Previous Route: | 176 |
| Next Type: | MO |
| Next Route: | 179 |
| Map Custom: | yes |
| Map Notes: | Route 177 highlighted in red |
Route 177 is a highway in Cape Girardeau County, Missouri, USA. Its northern terminus is at U.S. Route 61 at Fruitland, Missouri; its southern terminus is at Route 34/Route 74 in Cape Girardeau.