| State: | MO |
| Type: | MO |
| Route: | 106 |
| Map Custom: | yes |
| Map Notes: | MO 106 highlighted in red |
| Length Mi: | 46.298 |
| Direction B: | East |
| Direction A: | West |
| Terminus B: | at Ellington |
| Terminus A: | in Summersville |
| Previous Type: | MO |
| Previous Route: | 105 |
| Next Type: | MO |
| Next Route: | 107 |
Route 106 is a highway in the southern part of the US State of Missouri. Its eastern terminus is at Route 21 at Ellington; its western terminus is at Route 17 in Summersville. Route 106 runs through the eastern, mountainous Ozarks and through two sections of the Ozark National Scenic Riverways.
| State: | MO |
| Type: | MO-Spur |
| Route: | 106 |
| Location: | Deer Run State Forest |
| Length Mi: | 1.359 |
Spur Route 106 connects the main highway with Deer Run State Forest.