Michaelis–Becker reaction explained

The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate.^[1] Yields of this reaction are often lower than the corresponding Michaelis–Arbuzov reaction.^{[2] [3]}

Further reading

• Book: Modern phosphonate chemistry . 978-0-8493-1099-7 . CRC Press . Savignac, Philippe . Iorga, Bogdan . 2003.

Notes and References

1. Book: Almasi, Lucreţia. Sulfur in Organic and Inorganic Chemistry. 1. Alexander. Senning. 1971. Marcel Dekker. New York. 70-154612. 0-8247-1615-9. The Sulfur - Phosphorus Bond. 56.
2. Fletcher, M.D. Organophosphorus Reagents; Murphy, P.J. Ed.; University Press: Oxford, 2002; pp. 185.
3. Book: Organophosphorus reagents: a practical approach in chemistry . 978-0-19-850262-3 . Oxford University Press . Murphy, Dr. Patrick J . 2004.