| Mesolakkos | |
| Name Local: | Μεσόλακκος |
| Municunit: | Grevena |
| Population: | 30 |
| Population As Of: | 2021 |
| Coordinates: | 40.085°N 51.8°W |
| Postal Code: | 511 00 |
| Area Code: | +30-2462 |
| Licence: | PN |
| Elevation: | 610 |
Mesolakkos (before 1927: Ζυγόστι – Zygosti)[1] is a village of the Grevena municipality. At the 1997 local government reform it became part of the municipality of Grevena.[2] The 2021 census recorded 30 residents in the village. Mesolakkos is a part of the community of Kalochi.