| Mesnil-Lettre | |
| Commune Status: | Commune |
| Arrondissement: | Troyes |
| Canton: | Arcis-sur-Aube |
| Insee: | 10236 |
| Postal Code: | 10240 |
| Mayor: | Jean-Pierre Petitet[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 48.4567°N 4.2672°W |
| Elevation M: | 122 |
| Area Km2: | 8.89 |
Mesnil-Lettre (pronounced as /fr/) is a commune in the Aube department in north-central France.