| Official Name: | Mayfield Colony, South Dakota |
| Settlement Type: | Census-designated place |
| Pushpin Map: | South Dakota#USA |
| Pushpin Label: | Mayfield Colony |
| Coordinates: | 44.6942°N -97.5811°W |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | South Dakota |
| Subdivision Type2: | County |
| Subdivision Name2: | Clark |
| Area Footnotes: | [1] |
| Area Total Sq Mi: | 0.26 |
| Area Land Sq Mi: | 0.26 |
| Area Water Sq Mi: | 0.00 |
| Area Total Km2: | 0.67 |
| Area Land Km2: | 0.67 |
| Area Water Km2: | 0.00 |
| Population As Of: | 2020 |
| Population Footnotes: | [2] |
| Population Density Km2: | 218.18 |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 1778 |
| Postal Code Type: | ZIP Code |
| Postal Code: | 57278 (Willow Lake) |
| Area Code: | 605 |
| Blank Name: | FIPS code |
| Blank Info: | 46-41548 |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 2813009 |
| Population Total: | 146 |
| Unit Pref: | Imperial |
| Population Density Sq Mi: | 565.89 |
Mayfield Colony is a Hutterite colony[3] and census-designated place (CDP) in Clark County, South Dakota, United States. The population was 146 at the 2020 census.[4] It was first listed as a CDP prior to the 2020 census.
It is in the southeast part of the county, on the east shore of Dry Lake Number Two, 8miles northeast of Willow Lake and southeast of Clark, the county seat.