| Honorific-Prefix: | The Hon. |
| Matthew Henry Cochrane | |
| Office: | Senator for Wellington, Quebec |
| Predecessor: | John Sewell Sanborn |
| Successor: | William Mitchell |
| Term Start: | October 17, 1872 |
| Term End: | August 12, 1903 |
| Appointed: | John A. Macdonald |
| Birth Date: | 11 November 1823 |
| Birth Place: | Compton, Lower Canada |
| Death Place: | Compton, Quebec |
| Party: | Conservative |
Matthew Henry Cochrane (November 11, 1823 - August 12, 1903) was a Canadian industrialist, livestock breeder, and politician.
Born in Compton, Lower Canada, the eldest son of an Irish Anglican immigrant, James Cochrane, Cochrane was a cattle importer and breeder. He was appointed to the Senate on the advice of John Alexander Macdonald in October 1872 representing the senatorial division of Wellington, Quebec. A Conservative, he served almost 31 years until his death in 1903. His 1100acres ranch in Compton was one of the most well known in Canada and his annual auctions attracted ranches from all across North America and England. He was one of the founders of the Eastern Townships Bank and Cochrane Ranch in Alberta was one of the largest in the British Empire.
Cochrane, Alberta is named in his honour.[1]