| Party: | PS (1993–present) |
| Office: | Minister of Health |
| Primeminister: | António Costa |
| Term Start: | 10 September 2022 |
| Term End: | 2 April 2024 |
| Predecessor: | Marta Temido |
| Successor: | Ana Paula Martins |
| Term Start2: | 26 March 2024 |
| Birth Date: | 2 February 1964 |
| Birth Place: | Coimbra, Portugal |
| Spouse: | Alexandra Pinto |
| Alma Mater: | University of Porto |
| Occupation: | Doctor • Politician |
| Otherparty: | PCP (1978–1990) |
| Term Start3: | 10 March 2005 |
| Term End3: | 22 October 2015 |
| Constituency3: | Porto |
| Office4: | Member of the European Parliament |
| Constituency4: | Portugal |
| Term Start4: | 2 July 2019 |
| Term End4: | 10 September 2022 |
| Constituency2: | Porto |
| Office5: | Member of the Porto City Council |
| Term Start5: | 29 September 2013 |
| Term End5: | 26 September 2021 |
| Birth Name: | Manuel Francisco Pizarro de Sampaio e Castro |
| Term Start6: | 9 October 2005 |
| Term End6: | 30 January 2008 |
| Office7: | Member of the Porto Municipal Assembly |
| Term Start7: | 16 December 2001 |
| Term End7: | 9 October 2005 |
| Office8: | Member of the Ramalde Parish Assembly |
| Term Start8: | 12 December 1982 |
| Term End8: | 16 December 2001 |
Manuel Francisco Pizarro de Sampaio e Castro (born 2 February 1964) is a Portuguese politician of the Socialist Party who served as Minister of Health in Prime Minister António Costa's third cabinet from 2022 to 2024. He previously was a Member of the European Parliament from 2019 to 2022.[1]
Pizarro started his political career as a member of the Parish Council in Ramalde, Porto, firstly as a member of the Portuguese Communist Party and, from 1993, as a member of the Socialist Party.[2] He was firstly elected to parliament after the 2005 legislative election, being a candidate in Porto District.[3]
He ran for mayor of Porto twice, firstly in 2013 and secondly in 2017, losing both times to Rui Moreira.[4]
Pizzaro was elected as Member of the European Parliament after the 2019 European elections. In parliament, he served on the Committee on Employment and Social Affairs and the Committee on Fisheries.
In addition to his committee assignments, Pizzaro was part of the parliament's delegation for relations with Brazil.[5] He was also a member of the European Parliament Intergroup on Trade Unions[6] and the URBAN Intergroup.[7]
In September 2022, Pizzaro was appointed by Prime Minister António Costa to replace Marta Temido as Minister of Health, joining the XXIII Constitutional Government.[8]
On May 18, 2023, the Portuguese state broadcaster Rádio e Televisão de Portugal reported that Pizarro was under investigation by the Portuguese Public Prosecution Service.[9]