| Mane Skerry | |
| Map: | Antarctica |
| Location: | Antarctica |
| Coordinates: | -67.8333°N -85°W |
| Population: | Uninhabited |
| Country: | None |
| Treaty System: | Antarctic Treaty System |
Mane Skerry is a small island in the central part of Lystad Bay, off Horseshoe Island, Antarctica. It was named from association with nearby Mite Skerry; an initial misspelling of the phrase "might and main" became established at the Falkland Islands Dependencies Survey station in the years 1955–57.