MT1E explained
Metallothionein-1E is a protein that in humans is encoded by the MT1E gene.[1] [2] [3]
Further reading
- West AK, Stallings R, Hildebrand CE, etal . Human metallothionein genes: structure of the functional locus at 16q13. . Genomics . 8 . 3 . 513–8 . 1991 . 2286373 . 10.1016/0888-7543(90)90038-V .
- Le Beau MM, Diaz MO, Karin M, Rowley JD . Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia. . Nature . 313 . 6004 . 709–11 . 1985 . 3856101 . 10.1038/313709a0 . 1985Natur.313..709L . 4321473 .
- Carter AD, Felber BK, Walling MJ, etal . Duplicated heavy metal control sequences of the mouse metallothionein-I gene. . Proc. Natl. Acad. Sci. U.S.A. . 81 . 23 . 7392–6 . 1985 . 6095291 . 10.1073/pnas.81.23.7392 . 392152 . free .
- Kondo Y, Kuo SM, Lazo JS . Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum. . J. Pharmacol. Exp. Ther. . 270 . 3 . 1313–8 . 1994 . 7932184 .
- Pauwels M, van Weyenbergh J, Soumillion A, etal . Induction by zinc of specific metallothionein isoforms in human monocytes. . Eur. J. Biochem. . 220 . 1 . 105–10 . 1994 . 8119276 . 10.1111/j.1432-1033.1994.tb18603.x . free .
- Vandeghinste N, Proost P, De Ley M . Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. . Cell. Mol. Biol. (Noisy-le-grand) . 46 . 2 . 419–33 . 2000 . 10774930 .
- Nguyen A, Jing Z, Mahoney PS, etal . In vivo gene expression profile analysis of metallothionein in renal cell carcinoma. . Cancer Lett. . 160 . 2 . 133–40 . 2000 . 11053642 . 10.1016/S0304-3835(00)00534-6 .
- Oppermann B, Zhang W, Magabo K, Kantorow M . Identification and spatial analysis of metallothioneins expressed by the adult human lens. . Invest. Ophthalmol. Vis. Sci. . 42 . 1 . 188–93 . 2001 . 11133866 . 2957813 .
- Garrett SH, Belcastro M, Sens MA, etal . Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells . J. Toxicol. Environ. Health A . 64 . 4 . 343–55 . 2001 . 11693492 . 10.1080/152873901316981321 . 2001JTEHA..64..343G . 43143430 .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Izmailova E, Bertley FM, Huang Q, etal . HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages . Nat. Med. . 9 . 2 . 191–7 . 2003 . 12539042 . 10.1038/nm822 . 26145639 .
- Hawse JR, Cumming JR, Oppermann B, etal . Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses . Invest. Ophthalmol. Vis. Sci. . 44 . 2 . 672–9 . 2003 . 12556398 . 10.1167/iovs.02-0018 . 2825746 .
- Sens D, Rossi M, Park S, etal . Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2 . J. Toxicol. Environ. Health A . 66 . 21 . 2031–46 . 2003 . 14555400 . 10.1080/713853980 . 2003JTEHA..66.2031S .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
- Sun NN, Fastje CD, Wong SS, etal . Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line . Toxicology and Industrial Health . 19 . 7–10 . 157–63 . 2005 . 15747776 . 10.1191/0748233703th185oa . 14394243 .
- Lederer CW, Torrisi A, Pantelidou M, etal . Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis . BMC Genomics . 8. 26 . 2007 . 17244347 . 10.1186/1471-2164-8-26 . 1796866 . free .
Notes and References
- Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB . Human metallothionein genes are clustered on chromosome 16 . Proc Natl Acad Sci U S A . 81 . 17 . 5494–8 . Oct 1984 . 6089206 . 391732 . 10.1073/pnas.81.17.5494 . 1984PNAS...81.5494K . free .
- Schmidt CJ, Jubier MF, Hamer DH . Structure and expression of two human metallothionein-I isoform genes and a related pseudogene . J Biol Chem . 260 . 12 . 7731–7 . Jul 1985 . 10.1016/S0021-9258(17)39668-0 . 2581970 . free .
- Web site: Entrez Gene: MT1E metallothionein 1E.