MSTO1 explained

Protein misato homolog 1 is a protein that in humans is encoded by the MSTO1 gene.^{[1] [2]}

The MSTO1 gene is 5134 base pairs (located in chromosome 1) and the MSTO1 protein is 570 aminoacids in length. It is located in the outer membrane of the mitochondrion, and is involved in the regulation of mitochondrial distribution and morphology.^[3]

Structure

The misato protein contains an N-terminal misato segment II myosin-like domain and a central tubulin domain.^[3]

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Miklos GL, Yamamoto M, Burns RG, Maleszka R . An essential cell division gene of Drosophila, absent from Saccharomyces, encodes an unusual protein with tubulin-like and myosin-like peptide motifs . Proc. Natl. Acad. Sci. U.S.A. . 94 . 10 . 5189–94 . 1997 . 9144213 . 10.1073/pnas.94.10.5189 . 24654 . 1997PNAS...94.5189M . free .
• Hartley JL, Temple GF, Brasch MA . DNA Cloning Using In Vitro Site-Specific Recombination . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 10.1101/gr.143000 . 310948 .

Notes and References

1. Kuryshev VY, Vorobyov E, Zink D, Schmitz J, Rozhdestvensky TS, Munstermann E, Ernst U, Wellenreuther R, Moosmayer P, Bechtel S, Schupp I, Horst J, Korn B, Poustka A, Wiemann S . An anthropoid-specific segmental duplication on human chromosome 1q22 . Genomics . 88 . 2 . 143–51 . Jul 2006 . 16545939 . 10.1016/j.ygeno.2006.02.002 . free .
2. Web site: Entrez Gene: MSTO1 misato homolog 1 (Drosophila).
3. Kimura M, Okano Y . Human Misato regulates mitochondrial distribution and morphology . Exp. Cell Res. . 313 . 7 . 1393–404 . April 2007 . 17349998 . 10.1016/j.yexcr.2007.02.004 .