21S rRNA (uridine2791-2'-O)-methyltransferase explained

21S rRNA (uridine²⁷⁹¹-2'-O)-methyltransferase (MRM2 (gene), mitochondrial 21S rRNA methyltransferase, mitochondrial rRNA MTase 2) is an enzyme with systematic name S-adenosyl-L-methionine:21S rRNA (uridine²⁷⁹¹-2'-O-)-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uridine²⁷⁹1 in 21S rRNA

S-adenosyl-L-homocysteine + 2'-O-methyluridine²⁷⁹¹ in 21S rRNA

The enzyme catalyses the methylation of uridine²⁷⁹¹ of mitochondrial 21S rRNA.

Notes and References

1. Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C . MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase . The EMBO Journal . 21 . 5 . 1139–47 . March 2002 . 11867542 . 125888 . 10.1093/emboj/21.5.1139 .