| Lost Creek | |
| Map Size: | 300 |
| Pushpin Map: | USA Oregon |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of the mouth of Lost Creek in Oregon |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Oregon |
| Subdivision Type4: | County |
| Subdivision Name4: | Jackson |
| Source1: | Cascade Range |
| Source1 Location: | near Lost Lake, east of Medford |
| Source1 Coordinates: | 42.2869°N -122.5253°W |
| Source1 Elevation: | 4716feet[1] |
| Mouth: | South Fork Little Butte Creek |
| Mouth Location: | near Lake Creek |
| Mouth Coordinates: | 42.3864°N -122.5844°W[2] |
| Mouth Elevation: | 1824feet |
| Basin Size: | 17.2sqmi[3] |
Lost Creek is a tributary of the south fork of Little Butte Creek in Jackson County in the U.S. state of Oregon. Flowing north from near Lost Lake east of Medford, it enters the larger stream about 4miles upstream of the rural community of Lake Creek and about 20miles from the confluence of Little Butte Creek with the Rogue River. The only named tributary of Lost Creek is Coon Creek, which enters from the left.[4]
Lost Creek Bridge, a covered bridge, carries Lost Creek Road over the creek but is closed to vehicular traffic. The 39feet structure is the shortest covered bridge in Oregon.[5] It was added to the National Register of Historic Places in 1979.[6]