| Little Seal River | |
| Pushpin Map: | Canada Ontario |
| Pushpin Map Caption: | Location of the mouth of the Little Seal River in Ontario |
| Subdivision Type1: | Country |
| Subdivision Name1: | Canada |
| Subdivision Type2: | Province |
| Subdivision Name2: | Ontario |
| Subdivision Type3: | Region |
| Subdivision Name3: | Northeastern Ontario |
| Subdivision Type4: | District |
| Subdivision Name4: | Cochrane |
| Source1: | Unnamed muskeg |
| Source1 Coordinates: | 50.84°N -79.7811°W |
| Source1 Elevation: | 35m (115feet) |
| Mouth: | Kesagami River |
| Mouth Coordinates: | 50.9689°N -79.7158°W |
| Mouth Elevation: | 7m (23feet) |
| River System: | James Bay drainage basin |
The Little Seal River is a river in northern Cochrane District in Northeastern Ontario, Canada.[1] It is part of the James Bay drainage basin, and is a right tributary of the Kesagami River.
The river begins in unnamed muskeg, flows northeast then northwest, and reaches its mouth at the Kesagami River, just upstream of the mouth of the Seal River. The Kesagami River flows via the Harricana River to James Bay.