| Little Kesagami River | |
| Pushpin Map: | Canada Ontario |
| Pushpin Map Caption: | Location of the mouth of the Little Kesagami River in Ontario |
| Subdivision Type1: | Country |
| Subdivision Name1: | Canada |
| Subdivision Type2: | Province |
| Subdivision Name2: | Ontario |
| Subdivision Type3: | Region |
| Subdivision Name3: | Northeastern Ontario |
| Subdivision Type4: | District |
| Subdivision Name4: | Cochrane |
| Source1: | Little Kesagami Lake |
| Source1 Coordinates: | 49.7692°N -80.2872°W |
| Source1 Elevation: | 298m (978feet) |
| Mouth: | Kesagami River |
| Mouth Coordinates: | 49.9169°N -80.3292°W |
| Mouth Elevation: | 282m (925feet) |
| River System: | James Bay drainage basin |
The Little Kesagami River is a river in northern Cochrane District in Northeastern Ontario, Canada.[1] It is part of the James Bay drainage basin, and is a right tributary of the Kesagami River.
The river begins at Little Kesagami Lake just west of Ontario Highway 652 and flows north to its mouth at the Kesagami River. The Kesagami River flows via the Harricana River to James Bay.