The following is a list of the members of the 18th Knesset, elected on 10 February 2009.
| MK | Party | Replaced | Date | Notes | |
|---|---|---|---|---|---|
| Yulia Shamalov-Berkovich | Kadima | Haim Ramon | 2 July 2009 | Ramon retired from politics to go into business | |
| Einat Wilf | Labor Party | Ophir Pines-Paz | 10 January 2010 | Pines-Paz retired from politics | |
| Raleb Majadele | Labor Party | Yuli Tamir | 13 April 2010 | Tamir retired from politics | |
| Nino Abesadze | Kadima | Tzachi Hanegbi | 9 November 2010 | Hanegbi suspended following indictment | |
| Yisrael Eichler | United Torah Judaism | Meir Porush | 6 February 2011 | Porush resigned as part of a seat rotation agreement. | |
| Shachiv Shnaan | Labor Party | Matan Vilnai | 14 February 2012 | Vilnai resigned to become ambassador. | |
| Doron Avital | Kadima | Ze'ev Boim | 18 March 2011 | Death of Boim | |
| Zehava Gal-On | New Movement – Meretz | Haim Oron | 25 March 2011 | Oron resigned his seat | |
| Avi Duan | Kadima | Eli Aflalo | 25 January 2012 | Aflalo resigned his seat | |
| Yuval Tzelner | Kadima | Tzipi Livni | 3 May 2012 | Livni resigned her seat | |
| Akram Hasoon | Kadima | Gideon Ezra | 17 May 2012 | Ezra died of cancer | |
| Ahmed Dabbah | Kadima | Avi Dichter | 16 August 2012 | Dichter resigned to become a government minister | |
| Alali Adamso | Likud | Yossi Peled | 16 September 2012 | Peled resigned his seat | |
| Yoram Marciano | Labor Party | Amir Peretz | 9 December 2012 | Peretz resigned after he left the Labor Party to join Hatnuah |