| Weekend end date | Film | Total
weekend
gross | Openings |
|---|
| 1 | | Yes Man | $4,165,840 | Bolt (#4); Marley & Me (#5). |
| 2 | | $2,401,237 | Seven Pounds (#2); The Tale of Despereaux (#12); Igor (#19). |
| 3 | | Bride Wars | $3,129,086 | Role Models (#2); Hotel for Dogs (#8); Doubt (#14); The Wrestler (#16). |
| 4 | | Valkyrie | $1,946,778 | Gran Torino (#3); (#4); Revolutionary Road (#9). |
| 5 | | Gran Torino | $1,938,124 | Milk (#16); The Spirit (#17). |
| 6 | | $1,631,703 | Transporter 3 (#3); Changeling (#4); Pride and Glory (#19). |
| 7 | | He's Just Not That Into You | $4,696,514 | Ghost Town (#3); My Bloody Valentine 3D (#6); Rachel Getting Married (#16). |
| 8 | | $2,530,622 | The International (#2); Zack and Miri Make a Porno (#6); The Reader (#7). |
| 9 | | $1,571,324 | The Unborn (#4); Last Chance Harvey(#6); The Combination (#12); W. (#20). |
| 10 | | Watchmen | $3,584,253 | New in Town (#5); The Secret Life of Bees (#16); Dean Spanley (#19). |
| 11 | | Confessions of a Shopaholic | $2,749,412 | Notorious (#4); Friday the 13th (#5); Easy Virtue (#8); Love the Beast (#11). |
| 12 | | $1,641,750 | (#2); Duplicity (#3); 12 Rounds (#7); Two Fists, One Heart (#15); Blindness (#20). |
| 13 | | Knowing | $2,035,276 | The Uninvited (#5); Bottle Shock (#15). |
| 14 | | Monsters vs. Aliens | $3,875,854 | The Pink Panther 2 (#4); Inkheart (#7); Summer Hours (#16). |
| 15 | | 17 Again | $3,138,224 | The Boat That Rocked (#3); Race to Witch Mountain (#4); Dragonball Evolution (#6); Mary and Max (#13); Elegy (#15). |
| 16 | | Fast & Furious | $7,996,484 | No new films in the top 20. |
| 17 | | $3,030,528 | The Boy in the Striped Pajamas (#5); Fired Up (#7); Tulpan (#20). |
| 18 | | | $6,617,733 | Defiance (#3); (#12); Tenderness (#18). |
| 19 | | Star Trek | $4,657,564 | Ghosts of Girlfriends Past (#3); Samson and Delilah (#9); Der Baader Meinhof Komplex (#15); Synecdoche, New York (#20). |
| 20 | | Angels & Demons | $5,200,845 | Observe and Report (#5); (#11); Gomorra (#13). |
| 21 | | | $4,733,269 | What Just Happened (#10); Warren Miller's Children of Winter (#12); Lesbian Vampire Killers (#15). |
| 22 | | $3,356,034 | State of Play (#3); My Year Without Sex (#9); Adventureland (#15). |
| 23 | | Terminator Salvation | $7,740,052 | I Love You, Man (#3); Is Anybody There? (#11); Two Lovers (#17). |
| 24 | | The Hangover | $3,442,920 | Land of the Lost (#3); Sunshine Cleaning (#10); The Merchant of Venice (#20). |
| 25 | | The Proposal | $3,497,584 | Year One (#3); Disgrace (#11). |
| 26 | | | $13,647,361 | (#4); Coco avant Chanel (#8); New York (#13); Wake in Fright (#20). |
| 27 | | $6,269,589 | (#2); Kambakkht Ishq (#11); Last Ride (#15). |
| 28 | | Brüno | $5,861,291 | The Fox and the Child (#19). |
| 29 | | Harry Potter and the Half-Blood Prince | $14,330,931 | My Life in Ruins (#7); My Friends, My Loves (#18). |
| 30 | | $6,462,870 | Drag Me to Hell (#4), Cheri (#10), Red Cliff (#11), The Limits of Control (#17). |
| 31 | | Public Enemies | $3,151,046 | My Sister's Keeper (#3), Love Aaj Kal (#12), Cedar Boys (#17). |
| 32 | | The Ugly Truth | $3,303,733 | (#2), Coraline (#6), Beautiful Kate (#9). |
| 33 | | $2,286,545 | District 9 (#2), Orphan (#8), Bandslam (#9), Balibo (#11), Kaminey (#14). |
| 34 | | Inglourious Basterds | $3,058,434 | Dance Flick (#9), The September Issue (#12), Subdivision (#17), Adam (#18). |
| 35 | | $2,126,777 | The Taking of Pelham 123 (#2), The Young Victoria (#4), Fighting (#8), Ponyo (#13), Taking Woodstock (#19). |
| 36 | | Up | $2,111,655 | Aliens in the Attic (#4), Charlie & Boots (#5), The Soloist (#9). |
| 37 | | $2,567,822 | Funny People (#2), Push (#8), Sorority Row (#11). |
| 38 | | $3,387,603 | (500) Days of Summer (#3), G-Force (#5), Dil Bole Hadippa! (#15). |
| 39 | | $3,490,738 | Fame (#2), Surrogates (#3), Looking for Eric (#14). |
| 40 | | $3,042,822 | Mao's Last Dancer (#2), Wake Up Sid (#18). |
| 41 | | Couples Retreat | $2,971,485 | Julie & Julia (#4), Whip It (#7), Moon (#14). |
| 42 | | The Final Destination | $2,089,606 | Astro Boy (#6), Whatever Works (#12), Blue (#16), Departures (#20). |
| 43 | | Couples Retreat | $1,300,748 | Saw VI (#4), All About Steve (#7), An Education (#9), |
| 44 | | Michael Jackson's This Is It | $3,701,314 | The Imaginarium of Doctor Parnassus (#4), The Box (#8), London Dreams (#19). |
| 45 | | $1,878,725 | The Time Traveller's Wife (#2), A Christmas Carol (#3), Case 39 (#12), Genova (#14), (#15), Ajab Prem Ki Ghazab Kahani (#16). |
| 46 | | 2012 | $6,075,162 | The Boys Are Back (#5), Amelia (#8), Heer Ranjha (#20). |
| 47 | | | $16,099,648 | A Serious Man (#8), Kurbaan (#14), Amreeka (#20). |
| 48 | | $6,029,668 | Cloudy with a Chance of Meatballs (#3), The Invention of Lying (#4), De Dana Dan (#12), Topp Twins' Untouchable Girls (#19). |
| 49 | | Paranormal Activity | $2,710,512 | Where the Wild Things Are (#3), Zombieland (#6), The Informant! (#8), Paa (#20). |
| 50 | | $1,644,039 | Planet 51 (#7), 9 (#11), Away We Go (#13), (#17). |
| 51 | | Avatar | $11,962,308 | Broken Embraces (#11). |
| 52 | | $12,349,526 | Sherlock Holmes (#2), (#3), Old Dogs (#4), Did You Hear About the Morgans? (#5), The Lovely Bones (#7), Nowhere Boy (#14), The French Kissers (#19). | |
