Lactiplantibacillus plantarum PS128 explained

Lactiplantibacillus plantarum PS128 is a specific strain of Lactiplantibacillus plantarum, a bacterium of the genus Lactobacillus .

Lactiplantibacillus plantarum is a diverse species of lactic bacterium found in a wide range of ecological niches including plant substrates, meat, milk, as well as in the gastrointestinal tract of humans. Lactic bacteria are gram-positive, oxygen-tolerant anaerobes that have been used in food fermentation for hundreds of years.[1]

Safety

Lactiplantibacillus plantarum is "generally recognized as safe".[2] and included in the "qualified presumption of safety" list of the European Food Safety Authority.[3]

A study on Rett syndrome patients found that probiotic Lactiplantibacillus plantarum PS128 supplementation was safe, well-tolerated, and showed promising improvements in cognitive development and dystonia, suggesting potential as a complementary therapy for Rett syndrome.[4]

Notes and References

  1. Behera. Sudhanshu S.. Ray. Ramesh C.. Zdolec. Nevijo. 2018-05-28. Lactobacillus plantarum with Functional Properties: An Approach to Increase Safety and Shelf-Life of Fermented Foods. BioMed Research International. 2018. 1–18. 10.1155/2018/9361614. 29998137. 5994577. 2314-6133. free.
  2. Web site: 2020-08-04. Generally Recognized as Safe (GRAS). 2020-10-06. FDA. en.
  3. Koutsoumanis. Kostas. Allende. Ana. Alvarez-Ordóñez. Avelino. Bolton. Declan. Bover-Cid. Sara. Chemaly. Marianne. Davies. Robert. Cesare. Alessandra De. Hilbert. Friederike. Lindqvist. Roland. Nauta. Maarten. 2020. Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 12: suitability of taxonomic units notified to EFSA until March 2020. EFSA Journal. en. 18. 7. e06174. 10.2903/j.efsa.2020.6174. 1831-4732. 7331632. 32760463.
  4. Wong . Lee Chin . Hsu . Chia-Jui . Wu . Yen-Tzu . Chu . Hsu-Feng . Lin . Jui-Hsiang . Wang . Hsin-Pei . Hu . Su-Ching . Tsai . Ying-Chieh . Tsai . Wen-Che . Lee . Wang-Tso . September 2024 . Investigating the impact of probiotic on neurological outcomes in Rett syndrome: A randomized, double-blind, and placebo-controlled pilot study . Autism . en . 28 . 9 . 2267–2281 . 10.1177/13623613231225899 . 38361371 . 1362-3613.

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