LSM10 explained

U7 snRNA-associated Sm-like protein LSm10 is a protein that in humans is encoded by the LSM10 gene.^{[1] [2]}

Interactions

LSM10 has been shown to interact with LSM3.^{[3] [4]}

See also

• U7 small nuclear RNA

Further reading

• Dominski Z, Zheng LX, Sanchez R, Marzluff WF . Stem-loop binding protein facilitates 3'-end formation by stabilizing U7 snRNP binding to histone pre-mRNA . Molecular and Cellular Biology . 19 . 5 . 3561–70 . May 1999 . 10207079 . 84148 . 10.1128/mcb.19.5.3561.
• Dominski Z, Erkmann JA, Yang X, Sànchez R, Marzluff WF . A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing . Genes & Development . 16 . 1 . 58–71 . Jan 2002 . 11782445 . 155312 . 10.1101/gad.932302 .
• Pillai RS, Grimmler M, Meister G, Will CL, Lührmann R, Fischer U, Schümperli D . Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing . Genes & Development . 17 . 18 . 2321–33 . Sep 2003 . 12975319 . 196468 . 10.1101/gad.274403 .
• Hassel S, Eichner A, Yakymovych M, Hellman U, Knaus P, Souchelnytskyi S . Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry . Proteomics . 4 . 5 . 1346–58 . May 2004 . 15188402 . 10.1002/pmic.200300770 . 6773754 .
• Lehner B, Sanderson CM . A protein interaction framework for human mRNA degradation . Genome Research . 14 . 7 . 1315–23 . Jul 2004 . 15231747 . 442147 . 10.1101/gr.2122004 .
• Azzouz TN, Pillai RS, Däpp C, Chari A, Meister G, Kambach C, Fischer U, Schümperli D . Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes . The Journal of Biological Chemistry . 280 . 41 . 34435–40 . Oct 2005 . 16087681 . 10.1074/jbc.M505077200 . free . 21.11116/0000-0007-E5F1-6 . free .
• Wagner EJ, Marzluff WF . ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase . Molecular and Cellular Biology . 26 . 17 . 6702–12 . Sep 2006 . 16914750 . 1592837 . 10.1128/MCB.00391-06 .

Notes and References

1. Pillai RS, Will CL, Lührmann R, Schümperli D, Müller B . Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein . The EMBO Journal . 20 . 19 . 5470–9 . Oct 2001 . 11574479 . 125645 . 10.1093/emboj/20.19.5470 .
2. Web site: Entrez Gene: LSM10 LSM10, U7 small nuclear RNA associated.
3. Lehner B, Sanderson CM . A protein interaction framework for human mRNA degradation . Genome Research . 14 . 7 . 1315–23 . Jul 2004 . 15231747 . 442147 . 10.1101/gr.2122004 .
4. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .