LPAR4 explained

Lysophosphatidic acid receptor 4 also known as LPA₄ is a protein that in humans is encoded by the LPAR4 gene.^{[1] [2] [3]} LPA₄ is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).^[4]

See also

• Lysophospholipid receptor
• P2Y receptor

Further reading

• Adrian K, Bernhard MK, Breitinger HG, Ogilvie A . Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells. . Biochim. Biophys. Acta . 1492 . 1 . 127–38 . 2000 . 11004484 . 10.1016/S0167-4781(00)00094-4.
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 139241 . 10.1073/pnas.242603899 . 2002PNAS...9916899M . free .
• Noguchi K, Ishii S, Shimizu T . Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family. . J. Biol. Chem. . 278 . 28 . 25600–6 . 2003 . 12724320 . 10.1074/jbc.M302648200 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 528928 . 10.1101/gr.2596504 .
• Ross MT, Grafham DV, Coffey AJ, etal . The DNA sequence of the human X chromosome. . Nature . 434 . 7031 . 325–37 . 2005 . 15772651 . 2665286 . 10.1038/nature03440 . 2005Natur.434..325R .
• Liu T, Qian WJ, Gritsenko MA, etal . Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. . J. Proteome Res. . 4 . 6 . 2070–80 . 2006 . 16335952 . 1850943 . 10.1021/pr0502065 .

Notes and References

1. Web site: Entrez Gene: GPR23 G protein-coupled receptor 23.
2. Janssens R, Boeynaems JM, Godart M, Communi D . Cloning of a human heptahelical receptor closely related to the P2Y5 receptor . Biochem. Biophys. Res. Commun. . 236 . 1 . 106–12 . July 1997 . 9223435 . 10.1006/bbrc.1997.6895 .
3. O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF, Lynch KR, George SR . Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes . Gene . 187 . 1 . 75–81 . March 1997 . 9073069 . 10.1016/S0378-1119(96)00722-6.
4. Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J . January 2010 . LPA Receptors: Subtypes and Biological Actions . Annual Review of Pharmacology and Toxicology . 50 . 1 . 157–186 . 10.1146/annurev.pharmtox.010909.105753 . 20055701.