| José López Domínguez | |
| Office: | Prime Minister of Spain |
| Term Start: | 6 July 1906 |
| Term End: | 30 November 1906 |
| Predecessor: | Segismundo Moret |
| Successor: | Segismundo Moret |
| Birthname: | José López Domínguez |
| Nationality: | Spanish |
| Signature: | Firma de José López Domínguez.svg |
| Honorific Prefix: | The Most Excellent |
| Monarch2: | Alfonso XIII |
| Office2: | President of the Senate of Spain |
| Predecessor2: | Marquess of Pidal |
| Termstart2: | 9 October 1905 |
| Termend2: | 6 July 1906 |
| Successor2: | Eugenio Montero Ríos |
| Office3: | Under Secretary of the Presidency |
| 1Namedata3: | Francisco Serrano |
| 1Blankname3: | Regent |
| 2Blankname3: | Prime Minister |
| 2Namedata3: | Fracisco Serrano Juan Prim |
| 3Blankname3: | Minister of Grace and Justice |
| 3Namedata3: | Antonio Romero Ortiz Cristóbal Martín de Herrera |
| Monarch4: | Alfonso XII |
| Monarch5: | Alfonso XIII |
| Monarch6: | Alfonso XIII |
| Office4: | Minister of War of Spain |
| Termend3: | 26 June 1869 |
| Termstart3: | 10 October 1868 |
| Predecessor3: | Isidoro Lora |
| Successor3: | Feliciano Herreros de Tejada |
| Termstart4: | 13 October 1883 |
| Termend4: | 18 January 1884 |
| Termstart5: | 11 December 1892 |
| Termend5: | 23 March 1895 |
| Termstart6: | 6 July |
| Termend6: | 15 October 1906 |
| Primeminister4: | José Posada Herrera |
| Predecessor4: | Arsenio Martínez-Campos |
| Successor4: | Marquis of Miravalles |
| Predecessor5: | Marcelo Azcárraga Palmero |
| Predecessor6: | Agustín de Luque y Coca |
| Successor6: | Agustín de Luque y Coca |
| Primeminister5: | Práxedes Mateo Sagasta |
| Successor5: | Marcelo Azcárraga Palmero |
| Primeminister6: | Himself |
| Office7: | Minister of the Navy of Spain |
| Termstart7: | 11 December |
| Termend7: | 14 December 1892 |
| Monarch7: | Alfonso XIII |
| Primeminister7: | Práxedes Mateo Sagasta |
| Predecessor7: | José María Beránger |
| Successor7: | Pascual Cervera y Topete |
| Office8: | Captain General of Catalonia |
| Termstart8: | 20 July |
| Termend8: | 31 December 1874 |
| President8: | Francisco Serrano |
| Predecessor8: | Francisco Serrano Bedoya |
| Successor8: | Arsenio Martínez Campos |
José López Domínguez (29 November 1829, in Marbella – 17 October 1911, in Madrid), was a Spanish military officer and politician who was prime minister of Spain between 6 July and 30 November 1906.
As a lieutenant of the artillery, he participated in the pronunciamiento of Leopoldo O'Donnell in 1854. He was sent as observer to the Crimean War and the Second Italian War of Independence. In 1859 - 1860 he fought in the Spanish-Moroccan War and reached the rank of colonel.
He joined the Liberal Union Party and was elected as a deputy several times. Related to General Serrano, he participated with him in the Revolution of 1868 and the Battle of Alcolea, in which the loyalists under Manuel Pavía were defeated. López Dominguez was promoted to general.
In 1871, he became mariscal de campo and personal military advisor to King Amadeo I of Spain. In 1873, he was appointed commander of the Army of the North against the Carlists in the Third Carlist War, but in the same year, he was asked by Emilio Castelar to lay siege to Cartagena, where the Cantonal Revolution had broken out. He had the city intensively bombarded and, on 12 January 1874, Cartagena was retaken. He then returned to the north and liberated Bilbao, which was under siege by the Carlists.
In 1874, under the new Serrano government, he became captain general of Catalonia. In 1883, he was minister of war in the Posada Herrera government and, between 1892 and 1895, in the Sagasta government.
During the Second Melillan campaign, he became captain-general and was also the representative of Malaga in the Spanish senate, a chamber of which he became the president between 1905 and 1907.
In July 1906, aged 77, he became prime minister of Spain with a government supported by José Canalejas. In the first months, he was also minister of war. After a plot within his own party, led by Segismundo Moret, he was forced to resign after five months. After his resignation, he retired from politics
In 1908, he was given the Toison de Oro, or Order of the Golden Fleece.
He died on 17 October 1911 in Madrid.