Koen Creek is a stream in St. Francois County in the U.S. state of Missouri. It is a tributary of the Flat River.
The stream headwaters arise at 37.8242°N -90.4401°W and it flows generally northwest to its confluence with Flat River at 37.8695°N -90.5018°W on the east edge of Desloge adjacent to US Route 67.
Koen Creek has the name of the local Koen family.[1]