| Klein Letaba River | |
| Name Other: | Little Letaba River |
| Pushpin Map: | South Africa |
| Pushpin Map Caption: | Location of the Klein Letaba River's mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | South Africa |
| Subdivision Type3: | Region |
| Subdivision Name3: | Limpopo Province |
| Source1 Location: | Soutpansberg |
| Mouth: | Olifants River |
| Mouth Location: | Limpopo Province |
| Mouth Coordinates: | -23.6486°N 31.145°W |
| Tributaries Right: | Middle Letaba River, Koedoes River, Soeketse River |
Klein Letaba River is a tributary of the Letaba River, situated in Limpopo, South Africa. After its confluence with the Groot Letaba River on the western boundary of the Kruger National Park, it forms the Letaba River flowing through the whole width of the park.
The Klein Letaba tributaries like the Soeketse River and Koedoes River are wide, dry and sandy ditches for most of the year.