KCNG4 explained
Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene.[1] [2] The protein encoded by this gene is a voltage-gated potassium channel subunit.
Further reading
- Mederos Y, Schnitzler M, Rinné S, Skrobek L, etal . Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4. . J. Biol. Chem. . 284 . 7 . 4695–704 . 2009 . 19074135 . 10.1074/jbc.M808786200 . free .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Ottschytsch N, Raes AL, Timmermans JP, Snyders DJ . Domain analysis of Kv6.3, an electrically silent channel. . J. Physiol. . 568 . Pt 3 . 737–47 . 2005 . 16096342 . 10.1113/jphysiol.2005.090142 . 1464172 .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
Notes and References
- Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ . Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome . Proc Natl Acad Sci U S A . 99 . 12 . 7986–91 . Jun 2002 . 12060745 . 123007 . 10.1073/pnas.122617999 . 2002PNAS...99.7986O . free .
- Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X . International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels . Pharmacol Rev . 57 . 4 . 473–508 . Dec 2005 . 16382104 . 10.1124/pr.57.4.10 . 219195192 .