Judith Potashkin Explained
Judith Potashkin |
Workplaces: | Rosalind Franklin University of Medicine and Science |
Alma Mater: | State University of New York at Buffalo |
Thesis Title: | Isolation and characterization of residual nuclei from S̲a̲c̲c̲h̲a̲r̲o̲m̲y̲c̲e̲s̲ c̲e̲r̲e̲v̲i̲s̲i̲a̲e̲ |
Thesis Url: | https://www.worldcat.org/oclc/ |
Thesis Year: | 1985 |
Judith Ann Potashkin is an American professor at Rosalind Franklin University of Medicine and Science. She is best known for her research on diseases such as Parkinson's and Alzheimer's. She is an elected fellow of the American Association for the Advancement of Science.
Education and career
Potashkin has an undergraduate degree from Lehigh University (1977), and an M.S. in from Pennsylvania State University where she worked on the connection between ribosomal RNA synthesis and viruses.[1] In 1985, Potashkin earned her Ph.D. from the State University of New York at Buffalo working on residual nuclei in yeast.[2] Following her Ph.D. she was a postdoctoral scientist at Cold Spring Harbor Laboratory. She moved to Chicago Medical School in 1990 where she is a tenured professor.[3]
Research
Potashkin is known for her research on the role of RNA in neurodegenerative diseases. Her early research examined residual nuclei in Saccharomyces cerevisiae.[4] She went on to examine the genes involved in RNA splicing[5] and identified defects in RNA processing.[6] Her research on Parkinson's disease includes defining biomarkers,[7] [8] [9] characterizing dysregulated pathways,[10] and assessing the role of nutrition.[11] Her research also extends into investigations of Alzheimer's disease.[12]
Selected publications
- Santiago. Jose A.. Potashkin. Judith A.. 2013. Shared dysregulated pathways lead to Parkinson's disease and diabetes. Trends in Molecular Medicine. en. 19. 3. 176–186. 10.1016/j.molmed.2013.01.002. 23375873.
- Seidl. Stacey E.. Santiago. Jose A.. Bilyk. Hope. Potashkin. Judith A.. 2014-03-07. The emerging role of nutrition in Parkinson's disease. Frontiers in Aging Neuroscience. 6. 36. 10.3389/fnagi.2014.00036. 1663-4365. 3945400. 24639650. free.
- Santiago. Jose A.. Potashkin. Judith A.. 2015-02-17. Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson's disease. Proceedings of the National Academy of Sciences. en. 112. 7. 2257–2262. 10.1073/pnas.1423573112. 0027-8424. 4343174. 25646437. 2015PNAS..112.2257S. free.
- Santiago. Jose A.. Littlefield. Alyssa M.. Potashkin. Judith A.. 2016. Integrative transcriptomic meta-analysis of Parkinson's disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson's disease. Scientific Reports. en. 6. 1. 34579. 10.1038/srep34579. 2045-2322. 5041099. 27680512. 2016NatSR...634579S.
Awards and honors
Potashkin was elected a fellow of the American Association for the Advancement of Science in 2020.[13]
Notes and References
- An investigation of a possible mechanism of stimulation of ribosomal ribonucleic acid synthesis by simian virus 40 T-antigen.. 1979. English. Judith Ann. Potashkin. 79946151.
- Isolation and characterization of residual nuclei from S̲a̲c̲c̲h̲a̲r̲o̲m̲y̲c̲e̲s̲ c̲e̲r̲e̲v̲i̲s̲i̲a̲e̲. 1985. English. Judith Ann. Potashkin. 14878436.
- Web site: Judith A. Potashkin, PhD. 2021-11-04. Rosalind Franklin University. en.
- Potashkin. Judith A.. Huberman. Joel A.. 1986-07-01. Characterization of DNA sequences associated with residual nuclei of Saccharomyces cerevisiae. Experimental Cell Research. en. 165. 1. 29–40. 10.1016/0014-4827(86)90530-6. 3519258. 0014-4827.
- Potashkin. Judith. Naik. Karuna. Wentz-Hunter. Kelly. 1993-10-22. U2AF Homolog Required for Splicing in Vivo. Science. 262. 5133. 573–575. 10.1126/science.8211184. 8211184. 1993Sci...262..573P.
- 1990-02-01. A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing.. The EMBO Journal. 9. 2. 525–534. 10.1002/j.1460-2075.1990.tb08139.x. 0261-4189. Potashkin. J.. Frendewey. D.. 2406130. 551696.
- Chen-Plotkin. Alice S.. Albin. Roger. Alcalay. Roy. Babcock. Debra. Bajaj. Vikram. Bowman. Dubois. Buko. Alex. Cedarbaum. Jesse. Chelsky. Daniel. Cookson. Mark R.. Dawson. Ted M.. 2018-08-15. Finding useful biomarkers for Parkinson's disease. Science Translational Medicine. 10. 454. eaam6003. 10.1126/scitranslmed.aam6003. 6097233. 30111645.
- Santiago. Jose A.. Potashkin. Judith A.. 2015-02-17. Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson's disease. Proceedings of the National Academy of Sciences. en. 112. 7. 2257–2262. 10.1073/pnas.1423573112. 0027-8424. 4343174. 25646437. 2015PNAS..112.2257S. free.
- Potashkin. Judith A.. Santiago. Jose A.. Ravina. Bernard M.. Watts. Arthur. Leontovich. Alexey A.. 2012-08-27. Biosignatures for Parkinson's Disease and Atypical Parkinsonian Disorders Patients. PLOS ONE. en. 7. 8. e43595. 10.1371/journal.pone.0043595. 1932-6203. 3428307. 22952715. 2012PLoSO...743595P. free.
- Santiago. Jose A.. Potashkin. Judith A.. 2013. Shared dysregulated pathways lead to Parkinson's disease and diabetes. Trends in Molecular Medicine. en. 19. 3. 176–186. 10.1016/j.molmed.2013.01.002. 23375873.
- Seidl. Stacey. Santiago. Jose. Bilyk. Hope. Potashkin. Judith. 2014. The emerging role of nutrition in Parkinson's disease. Frontiers in Aging Neuroscience. 6. 36. 10.3389/fnagi.2014.00036. 1663-4365. 3945400. 24639650. free.
- Santiago. Jose A.. Potashkin. Judith A.. 2021-02-12. The Impact of Disease Comorbidities in Alzheimer's Disease. Frontiers in Aging Neuroscience. 13. 631770. 10.3389/fnagi.2021.631770. 1663-4365. 7906983. 33643025. free.
- Web site: December 17, 2020. Judith Potashkin, PhD, Elected AAAS Fellow. 2021-11-04. Rosalind Franklin University. en.