| John Guice | |
| Import: | yes |
| Position1: | Defensive back |
| Birth Date: | 10 October 1983 |
| Height Ft: | 5 |
| Height In: | 8 |
| Weight Lbs: | 175 |
| Nfldraftedyear: | 2007 |
| Nfldraftedround: | Undrafted |
| Playing Years1: | 2008–2009 |
| Playing Team1: | BC Lions |
| Career Footnotes: | |
| Cfl: | 1791 |
John Guice (born October 10, 1983) is a former Canadian football defensive back. He was signed by the BC Lions as a street free agent in 2008. He played college football for the UNLV Rebels.