| John A. Holmes High School | |
| Streetaddress: | 800 North Oakum Street |
| City: | Edenton |
| State: | North Carolina |
| County: | (Chowan County) |
| Zipcode: | 27932 |
| Country: | USA |
| Principal: | Sonya Rinehart |
| Staff: | 38.16 (FTE) |
| Ratio: | 15.51 |
| Type: | Public high school |
| Enrollment: | 592[1] |
| Enrollment As Of: | 2022-23 |
| Campus: | (Urban/Country)--> |
| Colors: | Blue, white and gold [2] |
| Nickname: | Aces |
| Website: | https://www.ecps.k12.nc.us/apps/pages/index.jsp?uREC_ID=4341681&type=d&pREC_ID=2536210 |
John A. Holmes High School is a public high school located in Edenton, North Carolina.[3] The school has a Junior Reserve Officers' Training Corps program.[4]