| Official Name: | Izabal Department |
| Native Name: | Departmento de Izabal |
| Native Name Lang: | es |
| Settlement Type: | Department of Guatemala |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Guatemala |
| Subdivision Type: | Country |
| Subdivision Name: | Guatemala |
| Seat Type: | Capital |
| Seat: | Puerto Barrios |
| Parts Type: | Municipalities |
| Parts: | 5 |
| Government Type: | Departmental |
| Leader Title: | Governor |
| Area Total Km2: | 9038 |
| Area Water Km2: | 590 |
| Population As Of: | 2018 |
| Population Footnotes: | [1] |
| Population Total: | 408688 |
| Population Density Km2: | 45 |
| Population Urban: | 167653 |
| Population Blank1 Title: | Ethnicities |
| Population Blank1: | Ladino Q'eqchi' Garífuna Afro-Caribbean |
| Population Blank2 Title: | Religions |
| Population Blank2: | Roman Catholicism Evangelicalism Maya |
| Utc Offset1: | -6 |
| Coordinates: | 15.7333°N -88.6°W |
| Iso Code: | GT-IZ |
Izabal (pronounced as /es/) is one of the 22 departments of Guatemala. Its coastal areas form part of the homeland of the Garifuna people.
Izabal is bordered to the north by Belize, to the northeast by the Gulf of Honduras, to the east by Honduras, and by the Guatemalan departments of Petén to the northwest, Alta Verapaz to the west, and Zacapa to the south.
The Izabal Department surrounds Lake Izabal (or Lago de Izabal), which is Guatemala's largest lake (about 48 km long and 24 km wide, with an area of about 590 km2). The Spanish Colonial fort of San Felipe, now a Guatemalan national monument, overlooks the point where the lake flows into the Río Dulce.
The small town of Izabal is on the south shore of the lake; before the construction of the ports of Livingston and Puerto Barrios in the 19th century this was Guatemala's main Caribbean Sea port and was the original seat of Izabal department; nowadays, however, Izabal town is a remote village that gets little traffic.
From the area around Lake Izabal, the Department of Izabal stretches along the Río Dulce to the coast of the Caribbean Sea.
The department of Izabal includes the ports of Puerto Barrios (the departmental seat), Santo Tomás de Castilla, Livingston and Guatemala's free trade zone Zolic. Izabal also includes the Pre-Columbian Maya ruins of Quirigua.