Isoserine Explained

Isoserine is a non-proteinogenic α-hydroxy-β-amino acid, and an isomer of serine. Non-proteinogenic amino are not part of the genetic code of any known organism and are only present in proteins if added post-translationally. Isoserine has only been produced synthetically.

The first documented synthesis of isoserine in a laboratory setting was by Miyazawa et al., who published their results in 1976.^[1]

See also

• Abiogenesis
• Miller–Urey experiment

Notes and References

1. Book: Ziora, Zyta . Amino Acids, Peptides and Proteins in Organic Chemistry, Volume 4: Protection, Reactions, Medicinal Chemistry, Combinatorial Synthesis . Hughes . Andrew B. . Skwarcynski . Mariusz . Kiso . Yoshiaki . 2011 . Medicinal Chemistry of α-Hydroxy-β-Amino Acids . https://books.google.com/books?id=uZK2i-FkeAUC&pg=SA6-PA3 . . Section 6.2.2: Synthesis of α-Hydroxy-β-amino acids . 978-3-527-63182-7 . 741558720 . 2017-06-10 . Google Books.