| Is-sur-Tille | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason de la ville d'Is-sur-Tille (21).svg |
| Arrondissement: | Dijon |
| Canton: | Is-sur-Tille |
| Insee: | 21317 |
| Postal Code: | 21120 |
| Mayor: | Thierry Darphin[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 47.5217°N 5.1161°W |
| Elevation M: | 284 |
| Elevation Min M: | 262 |
| Elevation Max M: | 408 |
| Area Km2: | 22.53 |
Is-sur-Tille (pronounced as /fr/) is a commune in the Côte-d'Or department of Bourgogne-Franche-Comté France.
Is-sur-Tille is located about twenty kilometers north of Dijon, on the river Ignon, close to its confluence with the Tille. To the west is a heavily forested limestone plateau with an elevation of over 400 meters. To the east is a humid clay plain sloping gently to the southeast of the Saône.