Iomeprol Explained

Tradename:Imeron, others
Routes Of Administration:Intravenous, intra-arterial
Atc Prefix:V08
Atc Suffix:AB10
Legal Us:Rx-only
Legal Us Comment:[1]
Legal Status:Rx-only
Metabolism:none
Elimination Half-Life:109±20 min
Excretion:Kidney
Cas Number:78649-41-9
Pubchem:3731
Drugbank:DB11705
Chemspiderid:3600
Unii:17E17JBP8L
Kegg:D01719
Chebi:31710
Iupac Name:1-N,3-N-bis(2,3-dihydroxypropyl)-5-(2-hydroxy-N-methylacetamido)-2,4,6-triiodobenzene-1,3-dicarboxamide
C:17
H:22
I:3
N:3
O:8
Smiles:Ic1c(c(I)c(c(I)c1N(C(=O)CO)C)C(=O)NCC(O)CO)C(=O)NCC(O)CO
Stdinchi:1S/C17H22I3N3O8/c1-23(9(29)6-26)15-13(19)10(16(30)21-2-7(27)4-24)12(18)11(14(15)20)17(31)22-3-8(28)5-25/h7-8,24-28H,2-6H2,1H3,(H,21,30)(H,22,31)
Stdinchikey:NJKDOADNQSYQEV-UHFFFAOYSA-N

Iomeprol, sold under the brand name Imeron among others, is a medication used as a radiocontrast agent in X-ray imaging.[2] [3]

It is classified as a water-soluble, nephrotrophic, low osmolar X-ray contrast medium. Low osmolar non-ionic agents are better tolerated and less likely to cause side effects than the high osmolar ionic agents.

The substance is not metabolized in the human body but excreted in unchanged form. It is decomposed slowly and can therefore accumulate in the environment.[4]

Society and culture

Legal status

Iomeprol was approved for medical use in the United States in November 2024.[5]

Notes and References

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/216017s000,216017s000lbl.pdf
  2. Book: Rossiter D . South African medicines formulary . 2014 . Health and Medical Pub. Group .of the South African Medical Association . Rondebosch, South Africa . 978-1-875098-30-9 . 11th . 869772940.
  3. Book: Austria-Codex. Haberfeld H . Iomeron 300 mg J/ml-Infusionsflasche. Österreichischer Apothekerverlag. Vienna. 2020. German.
  4. Pfundstein P, Martin C, Schulz W, Seitz W, Ruth KM, Wille A, Steinbach A, Flottmann D . IC-ICP/MS-Analytik. GIT Labor-Fachzeitschrift. January 2015. 29–31. de.
  5. Web site: Novel Drug Approvals for 2024 . U.S. Food and Drug Administration (FDA) . 1 October 2024 . 29 November 2024.