IFIT1 explained

Interferon-induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene.^{[1] [2] [3]}

Further reading

• Wathelet MG, Clauss IM, Nols CB, etal . New inducers revealed by the promoter sequence analysis of two interferon-activated human genes. . Eur. J. Biochem. . 169 . 2 . 313–21 . 1988 . 3121313 . 10.1111/j.1432-1033.1987.tb13614.x . free .
• Wathelet MG, Szpirer J, Nols CB, etal . Cloning and chromosomal location of human genes inducible by type I interferon. . Somat. Cell Mol. Genet. . 14 . 5 . 415–26 . 1988 . 3175763 . 10.1007/BF01534709 . 42406993 .
• Kusari J, Szabo P, Grzeschik KH, Sen GC . Chromosomal localization of the interferon-inducible human gene encoding mRNA 561. . J. Interferon Res. . 7 . 1 . 53–9 . 1987 . 3585080 . 10.1089/jir.1987.7.53 .
• Wathelet M, Moutschen S, Defilippi P, etal . Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons . Eur. J. Biochem. . 155 . 1 . 11–7 . 1986 . 3753936 . 10.1111/j.1432-1033.1986.tb09452.x . free .
• Chebath J, Merlin G, Metz R, etal . Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA . Nucleic Acids Res. . 11 . 5 . 1213–26 . 1983 . 6186990 . 10.1093/nar/11.5.1213 . 325791 .
• Rebouillat D, Marié I, Hovanessian AG . Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase . Eur. J. Biochem. . 257 . 2 . 319–30 . 1998 . 9826176 . 10.1046/j.1432-1327.1998.2570319.x . free .
• Guo J, Sen GC . Characterization of the Interaction between the Interferon-Induced Protein P56 and the Int6 Protein Encoded by a Locus of Insertion of the Mouse Mammary Tumor Virus . J. Virol. . 74 . 4 . 1892–9 . 2000 . 10644362 . 10.1128/JVI.74.4.1892-1899.2000 . 111667 .
• Guo J, Peters KL, Sen GC . Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection . Virology . 267 . 2 . 209–19 . 2000 . 10662616 . 10.1006/viro.1999.0135 . free .
• Guo J, Hui DJ, Merrick WC, Sen GC . A new pathway of translational regulation mediated by eukaryotic initiation factor 3 . EMBO J. . 19 . 24 . 6891–9 . 2001 . 11118224 . 10.1093/emboj/19.24.6891 . 305884 .
• Patzwahl R, Meier V, Ramadori G, Mihm S . Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive Hybridization . J. Virol. . 75 . 3 . 1332–8 . 2001 . 11152506 . 10.1128/JVI.75.3.1332-1338.2001 . 114039 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Gavrilov BG, Monastyrskaia GS, Velikodvorskaia TV, etal . [Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus] . Bioorg. Khim. . 29 . 2 . 175–80 . 2003 . 12708317 . 10.1023/a:1023260415910. 34300356 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 .
• Terenzi F, Hui DJ, Merrick WC, Sen GC . Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56 . J. Biol. Chem. . 281 . 45 . 34064–71 . 2006 . 16973618 . 10.1074/jbc.M605771200 . free .

Notes and References

1. Lafage M, Clauss I, Couez D, Simonetti J, Wathelet MG, Huez G . The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24 . Genomics . 13 . 2 . 458–60 . Jul 1992 . 1377167 . 10.1016/0888-7543(92)90272-T .
2. Wathelet MG, Clauss IM, Content J, Huez GA . The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family . FEBS Lett . 231 . 1 . 164–71 . Jun 1988 . 3360121 . 10.1016/0014-5793(88)80724-5 . 22937671 . free .
3. Web site: Entrez Gene: IFIT1 interferon-induced protein with tetratricopeptide repeats 1.