| Hugo B. Margáin | |
| Office: | Secretary of Finance and Public Credit |
| Term Start1: | 13 August 1970 |
| Term End1: | 29 May 1973 |
| President1: | Gustavo Díaz Ordaz Luis Echeverría |
| Predecessor1: | Antonio Ortiz Mena |
| Successor1: | José López Portillo |
| Birth Date: | 13 February 1913 |
| Birth Place: | Mexico City[1] |
| Death Place: | Mexico[2] |
| Party: | Institutional Revolutionary Party (PRI) |
| Spouse: | Margarita Charles |
| Parents: | César R. Margáin and María Teresa Gleason |
| Relations: | Manuel Sandoval Vallarta (brother-in-law) |
| Profession: | Diplomat and economist |
| Alma Mater: | National Autonomous University of Mexico (UNAM) |
Hugo B. Margáin Gleason (13 February 1913 -) was a Mexican economist, politician and diplomat who served as Secretary of Finance in the cabinet of Luis Echeverría (1970–73), as ambassador of Mexico to the United States (1964–70 and 1976–82), as ambassador of Mexico to the United Kingdom (1973–76) and as senator representing the Institutional Revolutionary Party (PRI, 1982–88).
. Roderic Ai Camp. Mexican Political Biographies, 1935-1993. University of Texas Press. 1995. 3rd. 434. 9780292711815.