Homeobox a cluster explained

Homeobox A cluster is a protein that in humans is encoded by the HOXA@ gene.^[1]

Further reading

• Soulier J, Clappier E, Cayuela JM, Regnault A, García-Peydró M, Dombret H, Baruchel A, Toribio ML, Sigaux F . HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL) . Blood . 106 . 1 . 274–86 . 2005 . 15774621 . 10.1182/blood-2004-10-3900 . free .
• Dik WA, Brahim W, Braun C, Asnafi V, Dastugue N, Bernard OA, van Dongen JJ, Langerak AW, Macintyre EA, Delabesse E . CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes . Leukemia . 19 . 11 . 1948–57 . 2005 . 16107895 . 10.1038/sj.leu.2403891 . free .
• Sessa L, Breiling A, Lavorgna G, Silvestri L, Casari G, Orlando V . Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster . RNA . 13 . 2 . 223–39 . 2007 . 17185360 . 1781374 . 10.1261/rna.266707 .
• Caudell D, Aplan PD . The role of CALM-AF10 gene fusion in acute leukemia . Leukemia . 22 . 4 . 678–85 . 2008 . 18094714 . 2366104 . 10.1038/sj.leu.2405074 .
• Van Vlierberghe P, van Grotel M, Tchinda J, Lee C, Beverloo HB, van der Spek PJ, Stubbs A, Cools J, Nagata K, Fornerod M, Buijs-Gladdines J, Horstmann M, van Wering ER, Soulier J, Pieters R, Meijerink JP . The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia . Blood . 111 . 9 . 4668–80 . 2008 . 18299449 . 2343598 . 10.1182/blood-2007-09-111872 .
• Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM . High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men . J. Bone Miner. Res. . 24 . 12 . 2039–49 . 2009 . 19453261 . 2791518 . 10.1359/jbmr.090524 .
• Lodder EM, Eussen BH, van Hassel DA, Hoogeboom AJ, Poddighe PJ, Coert JH, Oostra BA, de Klein A, de Graaff E . Implication of long-distance regulation of the HOXA cluster in a patient with postaxial polydactyly . Chromosome Res. . 17 . 6 . 737–44 . 2009 . 19672683 . 2759026 . 10.1007/s10577-009-9059-5 .
• Ester AR, Weymouth KS, Burt A, Wise CA, Scott A, Gurnett CA, Dobbs MB, Blanton SH, Hecht JT . Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot . Am. J. Med. Genet. A . 149A . 12 . 2745–52 . 2009 . 19938081 . 2795347 . 10.1002/ajmg.a.33130 .
• Ester AR, Weymouth KS, Burt A, Wise CA, Scott A, Gurnett CA, Dobbs MB, Blanton SH, Hecht JT . Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot . Am. J. Med. Genet. A . 149A . 12 . 2745–52 . 2009 . 19938081 . 2795347 . 10.1002/ajmg.a.33130 .

Notes and References

1. Web site: Entrez Gene: Homeobox A cluster. 2017-10-05.