HIP1R explained

Huntingtin-interacting protein 1-related protein is a protein that in humans is encoded by the HIP1R gene.^{[1] [2]}

Further reading

• Parker JA, Metzler M, Georgiou J, etal . Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. . J. Neurosci. . 27 . 41 . 11056–64 . 2007 . 17928447 . 6672856 . 10.1523/JNEUROSCI.1941-07.2007 .
• Bradley SV, Hyun TS, Oravecz-Wilson KI, etal . Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. . Hum. Mol. Genet. . 16 . 11 . 1279–92 . 2007 . 17452370 . 10.1093/hmg/ddm076 . free .
• Provençal N, Shink E, Harvey M, etal . Analysis of a variable number tandem repeat polymorphism in the huntingtin interacting protein-1 related gene for anticipation in bipolar affective disorder. . Prog. Neuropsychopharmacol. Biol. Psychiatry . 28 . 8 . 1299–303 . 2005 . 15588756 . 10.1016/j.pnpbp.2004.07.001 . 23161289 .
• Senetar MA, Foster SJ, McCann RO . Intrasteric inhibition mediates the interaction of the I/LWEQ module proteins Talin1, Talin2, Hip1, and Hip12 with actin. . Biochemistry . 43 . 49 . 15418–28 . 2005 . 15581353 . 10.1021/bi0487239 .
• Navarro-Lérida I, Martínez Moreno M, Roncal F, etal . Proteomic identification of brain proteins that interact with dynein light chain LC8. . Proteomics . 4 . 2 . 339–46 . 2004 . 14760703 . 10.1002/pmic.200300528 . 8868600 .
• Engqvist-Goldstein AE, Zhang CX, Carreno S, etal . RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery. . Mol. Biol. Cell . 15 . 4 . 1666–79 . 2004 . 14742709 . 10.1091/mbc.E03-09-0639 . 379265 .
• Hyun TS, Rao DS, Saint-Dic D, etal . HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains. . J. Biol. Chem. . 279 . 14 . 14294–306 . 2004 . 14732715 . 10.1074/jbc.M312645200 . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Legendre-Guillemin V, Metzler M, Charbonneau M, etal . HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain. . J. Biol. Chem. . 277 . 22 . 19897–904 . 2002 . 11889126 . 10.1074/jbc.M112310200 . free .
• Chopra VS, Metzler M, Rasper DM, etal . HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin. . Mamm. Genome . 11 . 11 . 1006–15 . 2001 . 11063258 . 10.1007/s003350010195 . 19956774 .
• Seki N, Muramatsu M, Sugano S, etal . Cloning, expression analysis, and chromosomal localization of HIP1R, an isolog of huntingtin interacting protein (HIP1). . J. Hum. Genet. . 43 . 4 . 268–71 . 1999 . 9852681 . 10.1007/s100380050087 . free .
• Ishikawa K, Nagase T, Suyama M, etal . Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. . DNA Res. . 5 . 3 . 169–76 . 1998 . 9734811 . 10.1093/dnares/5.3.169 . free .
• Puigvert A . Caliceal urodynamics. . Urol. Int. . 30 . 4 . 282–96 . 1976 . 1189126 . 10.1159/000279990 .

Notes and References

1. Brett TJ, Legendre-Guillemin V, McPherson PS, Fremont DH . Structural definition of the F-actin-binding THATCH domain from HIP1R . Nat Struct Mol Biol . 13 . 2 . 121–30 . Feb 2006 . 16415883 . 10.1038/nsmb1043 . 1456946 .
2. Web site: Entrez Gene: HIP1R huntingtin interacting protein 1 related.