| Official Name: | Gwin, Mississippi |
| Pushpin Map: | Mississippi#USA |
| Pushpin Label: | Gwin |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Mississippi |
| Subdivision Type2: | County |
| Subdivision Name2: | Holmes |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 115 |
| Coordinates: | 33.1736°N -90.2233°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 39169 |
| Area Code: | 662 |
| Blank Name: | GNIS feature ID |
Gwin is an unincorporated community located in Holmes County, Mississippi. Gwin is located on U.S. Highway 49E, south of Tchula.
The town was once an important station on the Illinois Central Railroad.
Gwin was the crew change point for all freight trains traveling between New Orleans and Memphis, and a hotel for train crews was located there. South of the town was a switching yard with six tracks, as well as a wye-junction where the track branched into a line which traveled east to Durant. Before electrical refrigeration was available for railcars, a large icing facility was located in Gwin, where ice was loading onto trains carrying perishable goods. In 1986, the railway moved its crew change point to McComb.[1] [2]