Guthrie is an unincorporated community in western Callaway County, in the U.S. state of Missouri. The community lies at the intersection of Missouri routes J and Y. New Bloomfield lies two miles south on Route J and the Pine Ridge Recreation Area of the Mark Twain National Forest along Cedar Creek is four miles east on Route Y.[1]
Guthrie was originally called Bigbee, and under the latter name was laid out in 1872 by B. S. Bigbee.[2] The present name is after John and Samuel N. Guthrie, early citizens. A post office called Bigbee was established in 1872, the name was changed to Guthrie in 1874, and the post office closed in 1954.[3]