The Greek Basketball League Best Defender, or Greek Basketball League Defensive Player of the Year, is an annual award for the best defensive player of each season of Greece's top-tier level professional basketball club league, the Greek Basketball League (GBL).
| Season | Best Defender | Club | Ref. | |
|---|---|---|---|---|
| Dimitris Diamantidis (2×) | ||||
 Josh Childress | ||||
| Dimitris Diamantidis (3×) | ||||
 Stéphane Lasme (2×) | ||||
| / Nick Calathes (2×) | ||||
| Kostas Papanikolaou | Olympiacos | |||
| / Nick Calathes (3×) | ||||
 Howard Sant-Roos (2×) | ||||
| / Thomas Walkup (2×) | ||||
Notes:
There was no awarding in the 2019–20, due to the coronavirus pandemic in Europe.