| Greatest Hits | |
| Type: | greatest |
| Artist: | Highway 101 |
| Cover: | Highway101GreatestHits.jpg |
| Released: | 1990 |
| Genre: | Country |
| Label: | Warner Brothers Records |
| Producer: | Paul Worley and Ed Seay |
| Prev Title: | Paint the Town |
| Prev Year: | 1989 |
| Next Title: | Bing Bang Boom |
| Next Year: | 1991 |
Greatest Hits is the first compilation album by American country music band Highway 101. This compilation of their previous hits also included two new songs: "Someone Else's Trouble Now" and "The Change." The rest of the album was filled with four songs from Highway 101, and two songs each from Highway 101² and Paint the Town.